Yap, G. L. R., Sachaphibulkij, K., Foo, S. L., Cui, J., Fairhurst, A. -M., & Lim, L. H. K. (2020). Annexin-A1 promotes RIG-I-dependent signaling and apoptosis via regulation of the IRF3-IFNAR-STAT1-IFIT1 pathway in A549 lung epithelial cells. CELL DEATH & DISEASE, 11(6)

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Cui, J., Morgan, D., Cheng, D. H., Foo, S. L., Yap, G. L. R., Ampomah, P. B., . . . Lim, L. H. K. (2020). RNA-Sequencing-Based Transcriptomic Analysis Reveals a Role for Annexin-A1 in Classical and Influenza A Virus-Induced Autophagy. CELLS, 9(6)

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Ampomah, P. B., & Lim, L. H. K. (2020). Influenza A virus-induced apoptosis and virus propagation.. Apoptosis, 25(1-2), 1-11

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Celhar, T., Lu, H. K., Benso, L., Rakhilina, L., Lee, H. Y., Tripathi, S., . . . Fairhurst, A. -M. (2019). TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner. FRONTIERS IN IMMUNOLOGY, 10

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Foo, S. L., Yap, G., Cui, J., & Lim, L. H. K. (2019). Annexin-A1-A Blessing or a Curse in Cancer?. TRENDS IN MOLECULAR MEDICINE, 25(4), 315-327

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Zharkova, O., Tay, S. H., Lee, H. Y., Shubhita, T., Ong, W. Y., Lateef, A., MacAry, P.A., Lim, L. H. K., Connolly, J.E.,  Fairhurst, A. -M. (2019). A Flow Cytometry-Based Assay for High-Throughput Detection and Quantification of Neutrophil Extracellular Traps in Mixed Cell Populations. CYTOMETRY PART A, 95A(3), 268-278

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Yoong, J., Alonso, S., Chan, C. W., Clement, M. -V., Lim, L. H. K., & Archuleta, S. (2019). Investing in gender equity in health and biomedical research: a Singapore perspective. LANCET, 393(10171), E21-E22

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Chua, S. C. J. H., Tan, H. Q., Engelberg, D., & Lim, L. H. K. (2019). Alternative experimental models for studying influenza proteins, host-virus interactions and anti-influenza drugs. Pharmaceuticals, 12(4). Review 

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Ampomah, P. B., Kong, W. T., Zharkova, O., Chua, S. C. J. H., Perumal Samy, R., & Lim, L. H. K. (2018). Annexins in Influenza Virus Replication and Pathogenesis.. Front Pharmacol, 9, 1282. 

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Celhar, T., Yasuga, H., Lee, H. Y., Zharkova, O., Tripathi, S., Thornhill, S. I., . . . Fairhurst, A. -M. (2018). Toll-Like Receptor 9 Deficiency Breaks Tolerance to RNA-Associated Antigens and Up-Regulates Toll-Like Receptor 7 Protein in Sle1 Mice. ARTHRITIS & RHEUMATOLOGY, 70(10), 1597-1609. 

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Bordoloi, D., Banik, K., Shabnam, B., Padmavathi, G., Monisha, J., Arfuso, F., . . . Kunnumakkara, A. B. (2018). TIPE Family of Proteins and Its Implications in Different Chronic Diseases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19(10)

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Ampomah, P. B., Moraes, L. A., Lukman, H. M., & Lim, L. H. K. (2018). Formyl peptide receptor 2 is regulated by RNA mimics and viruses through an IFN-b-STAT3-dependent pathway. FASEB Journal, 32(3), 1468-1478. doi:10.1096/fj.201700584RR

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Foo, H., Ng, K. P., Tan, J., Lim, L., Chander, R. J., Yong, T. T., & Kandiah, N. (2018). Interaction between APOE-4 and HMGB1 is associated with widespread cortical thinning in mild cognitive impairment. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 89(2), 224-226. doi:10.1136/jnnp-2017-315869

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Wang, C., Kar, S., Lai, X., Cai, W., Arfuso, F., Sethi, G., . . . Kumar, A. P. (2018). Triple negative breast cancer in Asia: An insider's view. CANCER TREATMENT REVIEWS, 62, 29-38. doi:10.1016/j.ctrv.2017.10.014

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Moraes, L. A., Ampomah, P. B., & Lim, L. H. K. (2018). Annexin A1 in inflammation and breast cancer: a new axis in the tumor microenvironment. CELL ADHESION & MIGRATION, 12(5), 417-423. 

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Moraes, L. A., Kar, S., Foo, S. L., Gu, T., Toh, Y. Q., Ampomah, P. B., . . . Lim, L. H. K. (2017). Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironment.  SCIENTIFIC REPORTS, 7

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Alli-Shaik, A., Wee, S., Lim, L. H. K., & Gunaratne, J. (2017). Phosphoproteomics reveals network rewiring to a pro-adhesion state in annexin-1-deficient mammary epithelial cells. BREAST CANCER RESEARCH, 19

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Gasser, S., Lim, L. H. K., & Cheung, F. S. G. (2017). The role of the tumour microenvironment in immunotherapy. ENDOCRINE-RELATED CANCER, 24(12), T283-T295

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Chen, L., Yuan, Y., Kar, S., Kanchi, M. M., Arora, S., Kim, J. E., . . . Kumar, A. P. (2017). PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers.. Mol Cancer Ther, 16(11), 2528-2542. 

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Chen, L., Yuan, Y., Kar, S., Kanchi, M. M., Arora, S., Kim, J. E., . . . Kumar, A. P. (2017). PPAR gamma Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers. MOLECULAR CANCER THERAPEUTICS, 16(11), 2528-2542

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Samy, R. P., Stiles, B. G., Franco, O. L., Sethi, G., & Lim, L. H. K. (2017). Animal venoms as antimicrobial agents. BIOCHEMICAL PHARMACOLOGY, 134, 127-138. doi:10.1016/j.bcp.2017.03.005

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Ningegowda, R., Shivananju, N. S., Rajendran, P., Basappa., Rangappa, K. S., Chinnathambi, A., . . . Priya, B. S. (2017). A novel 4,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazole derivative inhibits tumor cell invasion and potentiates the apoptotic effect of TNF alpha by abrogating NF-kappa B activation cascade. APOPTOSIS, 22(1), 145-157.

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Samy, R. P., Foo, S. L., Franco, O. L., Stiles, B. G., Kumar, A. P., Sethi, G., & Lim, L. H. (2017). Identification of natural peptides as a new class of antimalarial drugs by in silico approaches. Frontiers in Bioscience - Scholar, 9(1), 88-110. 

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Samy, R. P., Sethi, G., & Lim, L. H. K. (2016). A brief update on potential molecular mechanisms underlying antimicrobial and wound-healing potency of snake venom molecules. BIOCHEMICAL PHARMACOLOGY, 115, 1-9. 

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Tay, S. H., Lateef, A., Lim, Y. C., Ng, I. J. V., Koh, D. R., & Lim, L. H. K. (2016). Circulating microparticle double-stranded deoxyribonucleic acid in systemic lupus erythematosus. Annals of the Academy of Medicine Singapore, 45(8), 373-375.

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Arora, S., Lim, W., Bist, P., Perumalsamy, R., Lukman, H. M., Li, F., . . . Lim, L. H. K. (2016). Influenza A virus enhances its propagation through the modulation of Annexin-A1 dependent endosomal trafficking and apoptosis. CELL DEATH AND DIFFERENTIATION, 23(7), 1243-1256

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Chai, E. Z. P., Shanmugam, M. K., Arfuso, F., Dharmarajan, A., Wang, C., Kumar, A. P., . . . Sethi, G. (2016). Targeting transcription factor STAT3 for cancer prevention and therapy. PHARMACOLOGY & THERAPEUTICS, 162, 86-97. 

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Yuan, Y., Anbalagan, D., Lee, L. H., Samy, R. P., Shanmugam, M. K., Kumar, A. P., . . . Lim, L. H. K. (2016). ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and C-Myc to reduce breast cancer proliferation. ONCOTARGET, 7(19), 27007-27020

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Celhar, T., Pereira-Lopes, S., Thornhill, S. I., Lee, H. Y., Dhillon, M. K., Poidinger, M., . . . Fairhurst, A. -M. (2016). TLR7 and TLR9 ligands regulate antigen presentation by macrophages. INTERNATIONAL IMMUNOLOGY, 28(5), 223-232. 

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Zhang, J., Ahn, K. S., Kim, C., Shanmugam, M. K., Siveen, K. S., Arfuso, F., . . . Sethi, G. (2016). Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model. ANTIOXIDANTS & REDOX SIGNALING, 24(11), 575-589. 

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Samy, R. P., & Lim, L. H. K. (2015). DAMPs and influenza virus infection in ageing. AGEING RESEARCH REVIEWS, 24, 83-97.

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Nair, S., Arora, S., Lim, J. Y., Lee, L. H., & Lim, L. H. K. (2015). The regulation of TNF alpha production after heat and endotoxin stimulation is dependent on Annexin-A1 and HSP70. CELL STRESS & CHAPERONES, 20(4), 583-593. 

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Bist, P., Phua, Q. H., Shu, S., Yi, Y., Anbalagan, D., Lee, L. H., . . . Lim, L. H. K. (2015). Annexin-A1 controls an ERK-RhoA-NF kappa B activation loop in breast cancer cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 461(1), 47-53.

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Vanessa, K. H. Q., Julia, M. G., Wenwei, L., Michelle, A. L. T., Zarina, Z. R. S., Lina, L. H. K., & Sylvie, A. (2015). Absence of Annexin A1 impairs host adaptive immunity against Mycobacterium tuberculosis in vivo. Immunobiology, 220(5), 614-623. 

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Samy, R. P., Thwin, M. M., Stiles, B. G., Satyanarayana-Jois, S., Chinnathambi, A., Zayed, M. E., . . . Lim, L. H. K. (2015). Novel phospholipase A(2) inhibitors from python serum are potent peptide antibiotics. BIOCHIMIE, 111, 30-44. 

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Samy, R. P., Stiles, B. G., Chinnathambi, A., Zayed, M. E., Alharbi, S. A., Franco, O. L., . . . Sethi, G. (2015). Viperatoxin-II: A novel viper venom protein as an effective bactericidal agent. FEBS OPEN BIO, 5, 928-941. 

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LIM, H. (2015). Novel phospholipase A2 inhibitors from python serum are potent peptide antibiotics. Biochimie, 111.

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RAMAR PERUMALSAMY., GAUTAM SETHI., LIM, H., & CHOW, T. (2015). Microarray Analyses of Daboia russelli russelli Daboiatoxin Treatment of THP-1 Human Macrophages Infected with Burkholderia pseudomallei. CURRENT MOLECULAR MEDICINE, 15(10).

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Swa, H. L. F., Shaik, A. A., Lim, L. H. K., & Gunaratne, J. (2015). Mass spectrometry based quantitative proteomics and integrative network analysis accentuates modulating roles of annexin-1 in mammary tumorigenesis. PROTEOMICS, 15(2-3), 408-418. 

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Samy, R. P., Manikandan, J., Pachiappan, A., Ooi, E. E., Aw, L. T., Stiles, B. G., . . . Chow, V. T. (2015). Gene Microarray Analyses of Daboia russelli russelli Daboiatoxin Treatment of THP-1 Human Macrophages Infected with Burkholderia pseudomallei. CURRENT MOLECULAR MEDICINE, 15(10), 961-974. 

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GAUTAM SETHI., & LIM, H. (2015). Annexin-A1 controls an ERK-RhoA-NF�B activation loop in breast cancer cells. Biochemical and Biophysical Research Communications, 461(1)(1).

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Anbalagan, D., Yap, G., Yuan, Y., Pandey, V. K., Lau, W. H., Arora, S., . . . Lim, L. H. K. (2014). Annexin-A1 Regulates MicroRNA-26b*and MicroRNA-562 to Directly Target NF-kappa B and Angiogenesis in Breast Cancer Cells. PLOS ONE, 9(12), 20 pages. 

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Bist, P., Shu, S., Lee, H., Arora, S., Nair, S., Lim, J. Y., . . . Lim, L. H. K. (2013). Annexin-A1 Regulates TLR-Mediated IFN-beta Production through an Interaction with TANK-Binding Kinase 1. JOURNAL OF IMMUNOLOGY, 191(8), 4375-4382. 

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Manu, K. A., Shanmugam, M. K., Ong, T. H., Subramaniam, A., Siveen, K. S., Perumal, E., . . . Sethi, G. (2013). Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma. PLOS ONE, 8(3), 11 pages

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SHANMUG, M. K., LIM, H., & GAUTAM SETHI. (2013). Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma.. PLoS One.

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Swa, H. L. F., Blackstock, W. P., Lim, L. H. K., & Gunaratne, J. (2012). Quantitative Proteomics Profiling of Murine Mammary Gland Cells Unravels Impact of Annexin-1 on DNA Damage Response, Cell Adhesion, and Migration. MOLECULAR & CELLULAR PROTEOMICS, 11(8), 381-393

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Ng, F. S. P., Wong, K. Y., Guan, S. P., Mustafa, F. B., Kajiji, T. S., Bist, P., . . . Lim, L. H. K. (2011). Annexin-1-deficient mice exhibit spontaneous airway hyperresponsiveness and exacerbated allergen-specific antibody responses in a mouse model of asthma. CLINICAL AND EXPERIMENTAL ALLERGY, 41(12), 1793-1803

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Shanmugam, M. K., Manu, K. A., Ong, T. H., Ramachandran, L., Surana, R., Bist, P., . . . Sethi, G. (2011). Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model. INTERNATIONAL JOURNAL OF CANCER, 129(7), 1552-1563.

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Manu, K. A., Shanmugam, M. K., Rajendran, P., Li, F., Ramachandran, L., Hay, H. S., . . . Sethi, G. (2011). Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4. MOLECULAR CANCER, 10, 14 pages

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Bist, P., Leow, S. C., Phua, Q. H., Shu, S., Zhuang, Q., Loh, W. T., . . . Lim, L. H. K. (2011). Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-kappa B: implication in breast cancer metastasis. ONCOGENE, 30(28), 3174-3185.

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Chua, A. W. L., Hay, H. S., Rajendran, P., Shanmugam, M. K., Li, F., Bist, P., . . . Sethi, G. (2010). Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-kappa B activation in breast and pancreatic tumor cells. BIOCHEMICAL PHARMACOLOGY, 80(10), 1553-1562

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Mazzone, S. B., Lim, L. H. K., Wagner, E. M., Mori, N., & Canning, B. J. (2010). Sympathetic nerve-dependent regulation of mucosal vascular tone modifies airway smooth muscle reactivity. JOURNAL OF APPLIED PHYSIOLOGY, 109(5), 1292-1300. 

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Tay, P. N., Tan, P., Lan, Y., Leung, C. H. -W., Laban, M., Tan, T. C., . . . Hooi, S. C. (2010). Palladin, an actin-associated protein, is required for adherens junction formation and intercellular adhesion in HCT116 colorectal cancer cells. INTERNATIONAL JOURNAL OF ONCOLOGY, 37(4), 909-926. 

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Nair, S., Hande, M. P., & Lim, L. H. K. (2010). Annexin-1 protects MCF7 breast cancer cells against heat-induced growth arrest and DNA damage. CANCER LETTERS, 294(1), 111-117. 

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Kong, K. V., Leong, W. K., & Lim, L. H. K. (2009). Osmium Carbonyl Clusters Containing Labile Ligands Hyperstabilize Microtubules. CHEMICAL RESEARCH IN TOXICOLOGY, 22(6), 1116-1122.

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Kong, K. V., Leong, W. K., & Lim, L. H. K. (2009). Induction of apoptosis by hexaosmium carbonyl clusters. JOURNAL OF ORGANOMETALLIC CHEMISTRY, 694(6), 834-839.

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Ang, E. Z. -F., Nguyen, H. T., Sim, H. -L., Putti, T. C., & Lim, L. H. K. (2009). Annexin-1 Regulates Growth Arrest Induced by High Levels of Estrogen in MCF-7 Breast Cancer Cells. MOLECULAR CANCER RESEARCH, 7(2), 266-274. 

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Tan, Y., & Lim, L. H. K. (2008). trans-Resveratrol, an extract of red wine, inhibits human eosinophil activation and degranulation. BRITISH JOURNAL OF PHARMACOLOGY, 155(7), 995-1004

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Kong, K. V., Leong, W. K., Ng, S. P., Nguyen, T. H., & Lim, L. H. K. (2008). Osmium carbonyl clusters: A new class of apoptosis inducing agents. CHEMMEDCHEM, 3(8), 1269-1275. 

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Nguyen, T. -H., Mustafa, F. B., Pervaiz, S., Ng, F. S. P., & Lim, L. H. K. (2008). ERK1/2 activation is required for resveratrol-induced apoptosis in MDA-MB-231 cells. INTERNATIONAL JOURNAL OF ONCOLOGY, 33(1), 81-92.

 

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Mustafa, F. B., Ng, F. S. P., Nguyen, T. H., & Lim, L. H. K. (2008). Honeybee venom secretory phospholipase A(2) induces leukotriene production but not histamine release from human basophils. CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 151(1), 94-100. 

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Kong, K. V., Chew, W., Lim, L. H. K., Fan, W. Y., & Leong, W. K. (2007). Bioimaging in the mid-infrared using an organometallic carbonyl tag. BIOCONJUGATE CHEMISTRY, 18(5), 1370-1374. 

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Lim, L. H. K., & Pervaiz, S. (2007). Annexin 1: the new face of an old molecule. FASEB JOURNAL, 21(4), 968-975. doi:10.1096/fj.06-7464rev

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LIM, H. (2007). Organometallic Carbonyl Tags for Infrared Imaging of Cells. BIOCONJUGATE CHEMISTRY, 18(5).

 

 

Lim, L. H. K., Burdick, M. M., Hudson, S. A., Mustafa, F. B., Konstantopoulos, K., & Bochner, B. S. (2006). Stimulation of human endothelium with IL-3 induces selective basophil accumulation in vitro. JOURNAL OF IMMUNOLOGY, 176(9), 5346-5353. doi:10.4049/jimmunol.176.9.5346

 

Lim, L. H. K., & Wagner, E. M. (2003). Airway distension promotes leukocyte recruitment in rat trachael circulation. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 168(9), 1068-1074. doi:10.1164/rccm.200207-690OC

 

LIM, H. (2003). Leukocyte transit through the airway circulation. Archives of Physiology and Biochemistry, 111(4).

 

Matthay, M. A., Bhattacharya, S., Gaver, D., Ware, L. B., Lim, L. H. K., Syrkina, O., . . . Hubmayr, R. (2002). Ventilator-induced lung injury: in vivo and in vitro mechanisms. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 283(4), L678-L682. doi:10.1152/ajplung.00154.2002

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Lim, L. H. K., Bochner, B. S., & Wagner, E. M. (2002). Leukocyte recruitment in the airways: An intravital microscopic study of rat tracheal microcirculation. American Journal of Physiology - Lung Cellular and Molecular Physiology, 282(5 26-5). doi:10.1152/ajplung.00261.2001

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Henderson, R. B., Lim, L. H. K., Tessier, P. A., Gavins, F. N. E., Mathies, M., Perretti, M., & Hogg, N. (2001). The use of lymphocyte function-associated antigen (LFA)-1-deficient mice to determine the role of LFA-1, Mac-1, and alpha 4 integrin in the inflammatory response of neutrophils. JOURNAL OF EXPERIMENTAL MEDICINE, 194(2), 219-226. doi:10.1084/jem.194.2.219

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Oliani, S. M., Lim, L. H. K., Christian, H. C., Pell, K., Das, A. M., & Perretti, M. (2001). Morphological alteration of peritoneal mast cells and macrophages in the mouse peritoneal cavity during the early phases of an allergic inflammatory reaction. CELL BIOLOGY INTERNATIONAL, 25(8), 795-803. doi:10.1006/cbir.2001.0770

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Lim, L. H. K., Flower, R. J., Perretti, M., & Das, A. M. (2000). Glucocorticoid receptor activation reduces CD11b and CD49d levels on murine eosinophils - Characterization and functional relevance. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 22(6), 693-701. doi:10.1165/ajrcmb.22.6.3890

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Lim, L. H. K., Solito, E., Russo-Marie, F., Flower, R. J., & Perretti, M. (1998). Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: Effect of lipocortin 1. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 95(24), 14535-14539. doi:10.1073/pnas.95.24.14535

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LIM, H. (1998). Detachment of leukocytes adherent to murine post-capillary venules as a novel target to control inflammation: effect of lipocortin 1. Proceedings of the National Academy of Sciences of the United States of America, 95(24).

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Das, A. M., Lim, L. H. K., Flower, R. J., & Perretti, M. (1997). Dexamethasone reduces cell surface levels of CD11b on human eosinophils. MEDIATORS OF INFLAMMATION, 6(5-6), 363-367. doi:10.1080/09629359791505

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Szabo, C., Lim, L. H. K., Cuzzocrea, S., Getting, S. J., Zingarelli, B., Flower, R. J., . . . Perretti, M. (1997). Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects. JOURNAL OF EXPERIMENTAL MEDICINE, 186(7), 1041-1049. doi:10.1084/jem.186.7.1041